{"id":75738,"date":"2019-06-07T13:43:52","date_gmt":"2019-06-07T18:43:52","guid":{"rendered":"https:\/\/blog.familytreedna.com\/?p=75738"},"modified":"2023-01-10T10:22:30","modified_gmt":"2023-01-10T16:22:30","slug":"human-y-chromosome-testing-milestones","status":"publish","type":"post","link":"https:\/\/blog.familytreedna.com\/es\/human-y-chromosome-testing-milestones\/","title":{"rendered":"Big Y-700: The Forefront of Y Chromosome Testing"},"content":{"rendered":"

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Human Y Chromosome Testing Milestones<\/h3>\n

In 2013 we released the advanced Big Y test and since then, we’ve analyzed 32,000 Y chromosomes in ultra-high resolution. This has allowed us to identify hundreds of thousands of unique Y chromosome mutations. These mutations are the building blocks of the Y-DNA Haplotree. This is also known as the great family tree of all paternal lineages in the world.<\/span><\/p>\n

Mutations can sound scary. However, the genealogically relevant parts of the Y chromosome contain very few genes. It’s very unlikely that these mutations, or “variants”, have medical implications.<\/span><\/p>\n

The Y chromosome is passed down mostly unchanged from father to son. Small mutations occur randomly every few generations. It’s then passed down to all direct male descendants. Because of this, the genetic signature of every Y chromosome can be scanned to detect the paternal lineage. This all goes back to one man. The common paternal ancestor of all humanity. Commonly called Y-chromosomal Adam, he lived in Africa between 200,000 and 300,000 years ago.<\/span><\/p>\n

Recent Breakthroughs<\/h3>\n

Earlier this year, we announced an enhanced chemistry formula for Big Y. Big Y-700 provides even greater coverage of the Y chromosome. This allows us to detect even more mutations. As a result, all branches of the great tree of mankind are becoming further refined.<\/span><\/p>\n

The human Y chromosome contains about 56 million positions or base pairs. Of them, roughly 23 million base pairs (40%) are useful for phylogenetic analysis. In these 23 million positions, we’ve detected over 500,000 unique mutations in the total 32,000 Big Y testers. Our phylogenetic specialists work hard on refining the Haplotree as new results arrive. In May 2019, we passed 20,000 branches. The branches are defined by over 150,000 unique mutations. This makes our Haplotree the largest and most detailed phylogenetic tree of mankind in the world.\u00a0<\/span><\/p>\n

Quick View of the Y-DNA Haplotree and Block Tree.<\/strong>[\/vc_column_text][vc_gallery el_id=”gallery-963645″ medias=”75809,75812″ gutter_size=”3″ media_items=”title” screen_lg=”1000″ screen_md=”600″ screen_sm=”480″ single_overlay_opacity=”50″ single_padding=”2″][vc_single_image media=”75818″ caption=”yes” media_width_percent=”100″][vc_empty_space empty_h=”2″][vc_column_text]<\/p>\n

Statistics<\/h3>\n

More<\/em> than:<\/p>\n